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Sad as it might sound, I think we might have to stop worrying about the code.

That’s like that scene in the I, Robot movie when Will Smith’s character is asking the robot “can you turn an emtpy canvas into a work of art, or compose a symphony?” and the robot replies “can you?”.

Not trying to be provocative or anything, but ELIZA 60 years ago was already a better psychoanalist than many people I know.

`By your metrics, we achieved AGI in 1966.`

https://en.wikipedia.org/wiki/ELIZA


Need one for hair loss ASAP.


there is a AI designed drug for hair loss that i know of.

its slow-release oral minoxidil formulation called MINX. AI helped with the formulation [1].

its in in similar category as VDPHL01. Hundreds of millions if not a billion dollars has been invested into Veradermics, and their main product is VDPHL01 (also an extended-release oral formulation).

[1] https://x.com/anagenxyz/status/2071601868841595082


I’m on 0.5 to 1mg oral minoxidil daily for a few years now and it’s working great. Blood pressure benefits too.


> Blood pressure benefits too.

Speak for yourself, if mine goes any lower I’m going to pass out


Any other side effects? I’ve never even heard of this.


I’ve taken low dose oral min for a few years and it’s systemic, meaning it’ll make all your hair grow. I now have body hair where before it was never noticeable. “I’m hairy like monkey” as my kids say.


Can confirm. My torso and upper arms be sprouting like Robin Williams. Wasn’t like this before. Thankfully that’s easy to buzz off, and worth it to keep my head.


Indeed. My plans for a youthful Mohawk are being stymied by the lack of AI promised medical breakthroughs.

Wheres my follicles dammit?


Track KX-826, clascoterone, and VDPHL01


PP-405 too


Absci has a good asset coming out pretty soon that you could try to get on the trial.


Absci is bullshit


Already exists (finasteride), only problem is that it castrates you chemicallym


For everyone struggling with hair loss but concerned about side effects of Fin. Look into topical fin. It produces higher concentrations of the medication in the scalp and lower systemic concentration. Not perfect, but better.


About 2% of finasteride users experience these side effects, and they are reversible after discontinuation.


Apparently some users report persistent side effects even years after stopping the medication (post-finasteride syndrome).


How many of them can be accounted for by the natural rate of sexual dysfunction?

I've been taking it without significant side effects for ~15 years, so I'm not worried, although at this point it's losing its main effect as well.


yep that would be me


Are you familiar with Dr. Powers, there's hope


not familiar tbh, i will check it out sometime. thanks


Yep. Not everybody but enough to warrant vigilant monitoring and titration.


A good set of clippers.


> we’re approaching $800k in money spent on this rewrite.

That’s peanuts, if not the shells of the peanuts, for a project and company of this magnitude


Ohhhhh for a world where that's peanuts for an open source project.


How does that help 99.9% of all other companies though?


Some thoughts:

- just because it doesn’t help 99.9% of the companies today it doesn’t mean it won’t help them tomorrow

- 0.01% of the companies employ a much bigger percentage of people

- 99.9% of companies won’t need to do a project of this magnitude


This rewrite is showcased by Anthropic to sell AI rewrites to other companies.

If it turns out the rewrite cost stupid amounts of money and leads to a bad outcome, it's just a misleading ad.

We developers now need to explain that to illuminated management and colleagues.


So you think if a company can't spend 1 million USD on a rewrite which has almost zero impact on performance, possibly net negative on maintainability it also can't have 500k LOC codebase either? Oh come on...


> I guess I am one of those "architects" that imagines they need an actual date/time storage class instead of some stringly-typed text column that I hope will contain a parsable ISO8601 datetime string when I try to read it back.

To be honest if you're using JSON at any point in your stack you have the same issue.


I’ve literally calluses on my wrists from those edges.


So sad. Jurassic Park had a tremendous impact on me as a dino obsessed teenager ( was 13 when it came out). RIP.


It’s a unix system, I know this!

The file navigator she used was running on a silicon graphics machine, called fsn

https://preterhuman.net/software/file-system-navigator-fsn-s...


That I have a DevOps company working entirely on Linux can be directly attributed to realizing as a kid that Unix was a real thing and I needed to install it on my own computer. Interesting it was soon after this movie came out that FreeBSD and Linux were becoming popular.


A butterfly flaps its wings in Tokyo and we lose a leap second.


A few years back I got a couple of Adidas running shorts. Instead of the typical drawstring they had some continuous string. To this day I've no idea how it was supposed to be used, I just cut it off and voila, a regular drawstring.


You can tie the same knots without cutting the string. Just grab the two sides, pull them snug, then tie the knot. The fact that the “free ends” are connected at a distance doesn’t prevent the knot from holding like usual.

The advantage of the continuous loop is that it can’t end up inside the waistband during laundry.


Once I had a pair of the continuous loop sweats, I turned all my sweats into the same. My drawstrings always seem to end up getting retracted into the pants.



The current government has little chance to get re-elected, and the next one will revert most of these decisions.


It could be worse can only take a government so far. Eventually, just preaching to the choir catches up with you.


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